Testosterone Replacement Therapy in Chronic Spinal Cord Injury
Status:
Completed
Trial end date:
2012-12-01
Target enrollment:
Participant gender:
Summary
It has long been recognized that co-morbidity associated with multiple metabolic syndrome,
such as adverse body composition, insulin resistance and autonomic nervous system impairment,
may lead to significant increase in cardiovascular morbidity and mortality. It is unclear
whether the co-morbidity evident in this population are due directly to their immobility or
are the result of unfavorable changes in their underlying hormonal milieu. The purpose of
this study is to determine the effect of testosterone replacement therapy in hypogonadal
males on:
body composition, i.e. lean tissue and fat mass, glucose tolerance, resting energy
expenditure, autonomic-cardiovascular integrity, muscular strength, psychological assessment