Testosterone-Driven Growth-Hormone (GH) Secretion in Aging Men
Status:
Completed
Trial end date:
2008-08-01
Target enrollment:
Participant gender:
Summary
This study is being done to understand how testosterone, the major male sex hormone, controls
the pituitary gland's secretion of growth hormone (GH). GH is an important metabolic hormone,
which controls sugar; fat and protein use in the body and maintains muscle strength and bone
calcium content. Both testosterone and GH decline in older men. The age-related fall in these
hormones probably contributes to relative frailty, reduced quality of life, bone loss, muscle
wasting and impaired sexual function.