Testosterone-Dependent Effects on Protein Biomarkers From Healthy Males
Status:
Completed
Trial end date:
2015-06-01
Target enrollment:
Participant gender:
Summary
The study is designed to identify and validate new protein biomarkers in blood related to
testosterone activity. Thirty healthy young males underwent pharmaceutical castration to
lower testosterone levels. After three weeks the subjects received an intramuscular injection
of testosterone undecanoate. Blood samples from just before pharmaceutical castration, three
weeks after castration, and one week after injection of testosterone undecanoate were
collected representing normal testosterone levels, low testosterone levels, and testosterone
at eugonadal levels.