Overview

Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma

Status:
Completed
Trial end date:
2013-06-27
Target enrollment:
Participant gender:
Summary
This is a Phase I study, which means that the goal is to see if the combination of Temsirolimus and Sorafenib is safe in patients with Hepatocellular Carcinoma. Sorafenib is a standard treatment for Hepatocellular Carcinoma. Temsirolimus is used to treat cancer in the kidneys. It is hoped that the addition of Temsirolimus will make Sorafenib more effective against Advanced Hepatocellular Carcinoma, however this can not be guaranteed. The addition of Temsirolimus to Sorafenib is not an FDA approved treatment for Advanced Hepatocellular cancer.
Phase:
Phase 1
Details
Lead Sponsor:
University of California, San Francisco
Collaborator:
Northwestern University
Treatments:
Everolimus
Niacinamide
Sirolimus
Sorafenib