Ocular surface temperature of a normal person is around 34.6 degree centigrade. After
instilling the eye drop, depending on the temperature of the eye drop and the ocular surface,
the ocular surface temperature will temporally increase or decrease sightly. Warm feeling
will make blood vessels dilated and more blood will pass through to bring more blood flow out
of our body to the heated area of the body and makes cells more permeable. Therefore, heating
the ocular surface with heated eye mask after instilling artificial tears has the possibility
to improve drug permeability on the ocular surface.