Temperature-Sensitive Liposomal Doxorubicin and Hyperthermia in Treating Women With Locally Recurrent Breast Cancer
Status:
Terminated
Trial end date:
2011-04-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy, such as liposomal doxorubicin, work in different ways
to stop the growth of tumor cells, either by killing the cells or by stopping them from
dividing. Hyperthermia therapy kills tumor cells by heating them to several degrees above
normal body temperature. Giving temperature-sensitive liposomal doxorubicin together with
hyperthermia may kill more tumor cells.
PURPOSE: This phase I trial is studying the side effects and best dose of
temperature-sensitive liposomal doxorubicin when given together with hyperthermia in treating
women with locally recurrent breast cancer.