Temozolomide, Thalidomide, and Lomustine in Treating Patients With Unresectable Stage III or Stage IV Melanoma
Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy, such as temozolomide and lomustine, use different ways
to stop tumor cells from dividing so they stop growing or die. Thalidomide may stop the
growth of cancer by stopping blood flow to the tumor. Combining temozolomide and thalidomide
with lomustine may kill more tumor cells.
PURPOSE: Phase II trial to study the effectiveness of combining temozolomide and thalidomide
with lomustine in treating patients who have unresectable stage III or stage IV melanoma.