Overview

Temozolomide Plus Thalidomide in Treating Patients With Recurrent or Progressive Brain Tumor

Status:
Completed
Trial end date:
2006-07-20
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Thalidomide may stop the growth of cancer by stopping blood flow to the tumor. PURPOSE: Phase II trial to study the effectiveness of combining temozolomide and thalidomide in treating patients who have recurrent or progressive brain tumor.
Phase:
Phase 2
Details
Lead Sponsor:
North American Brain Tumor Consortium
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Collaborator:
National Cancer Institute (NCI)
Treatments:
Dacarbazine
Temozolomide
Thalidomide