Overview

Temozolomide Plus Irinotecan in Treating Patients With Recurrent Malignant Glioma

Status:
Completed
Trial end date:
2007-12-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: Phase I/II trial to study the effectiveness of temozolomide plus irinotecan in treating patients who have recurrent malignant glioma.
Phase:
Phase 1
Details
Lead Sponsor:
North American Brain Tumor Consortium
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Collaborator:
National Cancer Institute (NCI)
Treatments:
Dacarbazine
Irinotecan
Temozolomide