Overview

Temozolomide, Nedaplatin, Vincristine, and Radiotherapy as First-line Treatment in Newly Diagnosed Primary CNS Lymphoma

Status:
Unknown status

Trial end date:
2013-11-01

Target enrollment:

Participant gender:

Summary

In this trial, we will treat newly diagnosed PCNSL with temozolomide, nedaplatin, vincristine (TNV) as the replacement of high-dose methotrexate to combine with concurrent chemoradiotherapy. Our objective was to assess our treatment strategies' availability based on response rates, progression-free survival (PFS), median PFS, and toxicity.

Phase:

Phase 2

Details

Lead Sponsor:

Rongjie Tao

Collaborator:

National Natural Science Foundation of China

Treatments:

Dacarbazine
Nedaplatin
Temozolomide
Vincristine