Telmisartan, Amlodipine and Flow Mediated Dilation
Status:
Unknown status
Trial end date:
2011-10-01
Target enrollment:
Participant gender:
Summary
To show superior effects of the combination Telmisartan and Amlodipine (T and A) vs
Olmesartan and Hydrochlorothiazide (O and HCTZ) on endothelial dysfunction as measured by
flow mediated dilation (FMD) in hypertensive at risk patients beyond bloodpressure BP (equal
BP in both arms; target BP <140/90 mmHg (<130/80 mmHg for renally impaired and/ or diabetic
patients). To investigate the effects of T and A vs O and HCTZ in reducing arterial stiffness
and carotid atherosclerotic plaques.