The primary objective of the study is to determine if dimethyl fumarate (DMF) causes changes
in the abundance and diversity of commensal microbiota. The secondary objectives of this
study are as follows: To identify if there are differences in the gut microbiota composition
between patients that do or do not develop gastro intestinal (GI) adverse events (AEs), both
pre- and post DMF treatment and to examine if the resolution of GI AEs in DMF treated
patients is reflected in the gut microbiota.