Tea's Effect on Atherosclerosis Pilot Study (TEA Study)
Status:
Completed
Trial end date:
2005-04-01
Target enrollment:
Participant gender:
Summary
The researchers propose a pilot study of the effect of long-term tea intake on
atherosclerosis. Thirty patients at high risk for cardiovascular disease will be recruited
and randomized to a six-month period of consumption of 3 cups per day of either tea, supplied
as black tea solids readily dissolved in hot or cold liquid, or water.
At baseline and after 6 months, atherosclerosis in the aorta will be assessed using magnetic
resonance imaging. The primary outcomes of this pilot study will be compliance with tea
intake and 2 MRI examinations. As secondary outcomes, standard and novel cardiovascular risk
markers, including inflammatory, prothrombotic, fibrinolytic, vascular and metabolic factors
will be measured.
If successful, this pilot study will form the basis for a larger, long-term randomized trial
to determine the effect of tea consumption on progression of atherosclerosis.
Phase:
N/A
Details
Lead Sponsor:
Beth Israel Deaconess Medical Center
Collaborator:
National Center for Complementary and Integrative Health (NCCIH)