Overview

Targeting Pulsatile Load to Increase Exercise Capacity and Quality of Life After Aortic Valve Replacement for Severe Aortic Stenosis (PULSE AS)

Status:
Completed
Trial end date:
2019-05-23
Target enrollment:
Participant gender:
Summary
The current trial is designed to assess the safety and efficacy of sustained oral administration of inorganic nitrate in patients with severe aortic stenosis and to assess the mechanisms by which inorganic nitrate enhances oxygen uptake and exercise capacity in this population.
Phase:
Phase 2
Details
Lead Sponsor:
University of Pennsylvania