Overview

Targeting Pulmonary Perfusion in Alpha-1 Antitrypsin Deficiency

Status:
Completed
Trial end date:
2020-10-01
Target enrollment:
Participant gender:
Summary
The aim of this study is to test whether aspirin improves endothelial function in alpha-1 antitrypsin deficiency-associated lung disease, measured by pulmonary microvascular blood flow on magnetic resonance imaging (MRI) and with apoptotic endothelial microparticles.
Phase:
Phase 2
Details
Lead Sponsor:
Columbia University
Collaborators:
Alpha-1 Foundation
Stony Wold-Herbert Fund, Inc.
Treatments:
Alpha 1-Antitrypsin
Aspirin
Protein C Inhibitor