Targeted Levothyroxine Dosing in Infants With Congenital Hypothyroidism
Status:
Completed
Trial end date:
2016-05-01
Target enrollment:
Participant gender:
Summary
This is a clinical study comparing targeted levothyroxine dosing based on thyroid anatomy as
visualized on ultrasound (normal vs. ectopic/sublingual vs. athyreosis) to empiric
levothyroxine dosing in infants with congenital hypothyroidism. Patients enrolled in the
study for targeted dosing will be compared to controls obtained by retrospective chart
review. The main outcome is to determine if there is a difference in the frequency of
over-treatment and under-treatment during the first 6 months of therapy.