Targeted Blood-pressure Management and Acute Kidney Injury After Coronary Artery Bypass Surgery
Status:
Recruiting
Trial end date:
2025-07-01
Target enrollment:
Participant gender:
Summary
Acute renal injury (AKI) is a common complication after cardiac surgery and is associated
with worse outcomes. It is now realized that intraoperative hypotension is an important risk
factor for the development of AKI. In a recent randomized controlled trial of patients
undergoing major noncardiac surgery, intraoperative individualized blood-pressure management
reduced the incidence of postoperative organ dysfunction. The investigators hypothesize that,
for patients undergoing off-pump CABG, targeted blood-pressure management during surgery may
also reduce the incidence of postoperative AKI.