Target Engagement for Oxytocin: Dose Ranging Study

• Status: Completed
• Trial end date: 2017-07-01
• Target enrollment: 0
• Participant gender: All

Summary

This study will evaluate the effect of 8 doses of intranasal oxytocin or placebo on two proposed measures of target engagement in brain. The targets are (1) the suppression of a particular wave form (mu) on the electroencephalogram (EEG) while subjects observe a socially relevant form of motion and (2) pupil dilation will subjects identify faces showing different emotions.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of California, Los Angeles
• Treatments: Oxytocin

Criteria

Inclusion Criteria:

• Schizophrenia, Schizoaffective Disorder, Delusional Disorder

• Able to cooperate with study procedures

Exclusion Criteria:

• Serious medical condition or substance use

• Pregnancy