Overview

Tamoxifen and Clomiphene Citrate in Mild Stimulation IVF

Status:
Unknown status
Trial end date:
2019-03-01
Target enrollment:
0
Participant gender:
Female
Summary
The purpose of this prospective cohort study is to compare IVF outcome between tamoxifen and clomiphene citrate in mild stimulation.
Phase:
Phase 4
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Collaborator:
Sun Yat-sen University
Treatments:
Chorionic Gonadotropin
Citric Acid
Clomiphene
Enclomiphene
Tamoxifen
Zuclomiphene
Criteria
Inclusion Criteria:

1. age between 37 and 42;

2. BMI≤23kg/m2;

3. ≤3 oocytes with a conventional stimulation protocol;

4. AFC<5 follicles or AMH<1.1 ng/ml on the day 1 to 5 of the menses;

5. Cause of Infertiity: tubal factor, male factor, diminished ovarian reserve.

Exclusion Criteria:

1. endormetrial polyp, endormetrial cancer,intrauterine adhesions,uterine fibroids that
affects uterine cavity

2. Endometriosis, adenomyosis

3. The diameter of Hydrosalpinx >2cm