Tamoxifen, Ovarian Ablation, and/or Chemotherapy in Treating Women With Stage I, Stage II, or Stage IIIA Breast Cancer
Status:
Completed
Trial end date:
2007-04-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Estrogen can stimulate the growth of breast cancer cells. Hormone therapy using
tamoxifen may fight breast cancer by blocking the uptake of estrogen. Combination
chemotherapy uses different ways to stop tumor cells from dividing so they stop growing or
die. Combining hormone therapy with chemotherapy may kill more tumor cells.
PURPOSE: Randomized phase III trial to compare the effectiveness of tamoxifen with or without
chemotherapy and/or ovarian ablation in treating women with stage I, stage II, or stage IIIA
breast cancer.
Phase:
Phase 3
Details
Lead Sponsor:
Institute of Cancer Research, United Kingdom
Collaborators:
Cancer Research Campaign Clinical Trials Centre Scottish Cancer Therapy Network Yorkshire Regional Clinical Trials Research Unit