Tamoxifen Following Combination Chemotherapy in Treating Women With Operable Invasive Breast Cancer
Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
RATIONALE: Estrogen can stimulate the growth of breast cancer cells. Hormone therapy using
tamoxifen may fight breast cancer by blocking the uptake of estrogen. Combining combination
chemotherapy with hormone therapy may kill more tumor cells.
PURPOSE: Randomized phase III trial to compare the effectiveness of combination chemotherapy
with or without tamoxifen in treating women with stage I or stage II breast cancer that can
be surgically removed.