Tailored Therapy for Helicobacter Pylori in Children

• Status: Unknown status
• Trial end date: 2016-07-01
• Target enrollment: 0
• Participant gender: All

Summary

This study is designed to compare the eradication rates，safety and compliance of tailored therapy to those of standard triple therapy in children with H. pylori infection. The primary purpose is to compare the eradication rates of children with H. pylori infection treated with tailored therapy to those treated with standard triple therapy. The secondary purpose is to evaluate the safety, compliance and factors that might affect eradication rates.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Beijing Children's Hospital
• Treatments: Amoxicillin; Clarithromycin; Esomeprazole; Metronidazole; Omeprazole; Rabeprazole

Criteria

Inclusion Criteria:

• Clinical diagnosis of H. pylori infection.

• Presence of upper gastrointestinal symptoms.

• Referred for upper endoscopy at Beijing Children's Hospital

Exclusion Criteria:

• Presence of endoscopy contraindications

• The administration of any drug that could influence the study results including proton pump inhibitors, H2-receptor blockers, bismuth salts and antibiotics within the previous four weeks;

• Gastrointestinal malignancy;

• Previous gastric or esophageal surgery;

• Severe concomitant diseases

• History of allergy to any of the study drugs;