Tadalafil and Nesiritide as Therapy in Pre-clinical Heart Failure
Status:
Completed
Trial end date:
2014-08-01
Target enrollment:
Participant gender:
Summary
This study is being done to determine the effects of subcutaneous (under the skin) injection
of human B-type natriuretic factor (BNP), Natrecor (nesiritide), a hormone produced by the
heart, in combination with Tadalafil on:
- The pumping function of the heart
- Kidney function
- Hormonal function (levels of different hormones in your blood) in persons with lower
pumping function of their heart.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Mayo Clinic
Collaborators:
National Center for Research Resources (NCRR) National Heart, Lung, and Blood Institute (NHLBI)