Tacrine Effects on Cocaine Self-Administration and Pharmacokinetics
Status:
Withdrawn
Trial end date:
2013-11-01
Target enrollment:
Participant gender:
Summary
No medications are currently available for treatment of psychostimulant addiction, a
compulsive preoccupation with use of cocaine and related compounds. Tacrine, a medication
that is currently prescribed for Alzheimer's disease, can decrease the amount of cocaine
injections that laboratory animals choose to inject by vein. This project will determine if
tacrine can also decrease cocaine-motivated behavior for human subjects in a laboratory
setting.