TRANexamic Acid to Reduce Bleeding in BURN Surgery
Status:
Recruiting
Trial end date:
2021-09-01
Target enrollment:
Participant gender:
Summary
Excision and grafting in burn patients can lead to severe blood loss. A preliminary study
conducted in Saint Joseph Saint Luc Hospital showed that the total median blood loss was 1412
mL (1). Transfused patients had a total median blood loss of 2468 mL and an average number of
4 packed red blood cells (PRBC) administered.
Among the various methods that help limit blood loss, tranexamic acid, which has been proved
useful in traumatology and surgery, has not been sufficiently studied in burn patients. A
preliminary study in 27 burned patients showed a reduction of blood loss with tranexamic acid
(2).
Objective of TRANBURN study is to demonstrate that tranexamic acid help limit blood loss and
reduces the use of blood products.