Overview

TMC278-TiDP6-C136: Effect of TMC278 on Ethinylestradiol and Norethindrone in Healthy Women.

Status:
Completed
Trial end date:
2008-12-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to investigate the pharmacokinetic interaction between the combination of ethinylestradiol and norethindrone and TMC278 25 mg once daily. Pharmacokinetics means how the drug is absorbed into the bloodstream, distributed in the body and eliminated from the body. Furthermore the short-term safety and tolerability (how well the body tolerates the drug) of co-administration of TMC278 and ethinylestradiol and norethindrone, in healthy women, will be assessed.
Phase:
Phase 1
Details
Lead Sponsor:
Tibotec Pharmaceuticals, Ireland
Treatments:
Ethinyl Estradiol
Mestranol
Norethindrone
Norethindrone acetate
Norethindrone acetate, ethinyl estradiol, ferrous fumarate drug combination
Norinyl
Rilpivirine