Overview TKI 258 in Von Hippel-Lindau Syndrome (VHL) Status: Terminated Trial end date: 2015-12-01 Target enrollment: Participant gender: Summary The goal of this clinical research study is to learn if dovitinib can safely be given to patients who have VHL with a measurable hemangioblastoma (tumor of the central nervous system). The effects of this drug on the disease will also be studied. Phase: Phase 2 Details Lead Sponsor: M.D. Anderson Cancer CenterCollaborator: Novartis