TIVA vs TXA in Sinus Surgery to Evaluate Operative Blood Loss and Surgical Field Quality
Status:
Not yet recruiting
Trial end date:
2025-07-01
Target enrollment:
Participant gender:
Summary
The goal of this interventional study is to compare the efficacy (surgical field quality and
intra-operative blood loss) or cost of TIVA alone to general inhalational anesthetics with
intravenous TXA in patient participants who are undergoing endoscopic sinus surgery.
The main questions the study aims to answer are:
- Is the surgical field quality better when using TIVA alone compared to general
inhalational anesthetics with intravenous TXA?
- Is one method more financially advantageous to the participant and the institution
compared to the other method?
Participants will be randomized into one of the two anesthesia cohorts prior to sinus
surgery. One group will be given total intravenous anesthesia (TIVA) alone and the other will
be given intravenous tranexamic acid (TXA) followed by general inhalational anesthesia.
Researchers will compare the TIVA group to the TXA group to see if one group exhibits a
better surgery field viewing quality through a subjective evaluation and measurement of blood
loss and also which anesthesia regimen is most cost effective upon conducting a cost
analysis.
Phase:
N/A
Details
Lead Sponsor:
Our Lady of the Lake Hospital
Collaborator:
Louisiana State University Health Sciences Center in New Orleans