TIVA vs Inhalational Mode of Anaesthesia

• Status: Completed
• Trial end date: 2019-12-30
• Target enrollment: 0
• Participant gender: All

Summary

Sevoflurane based inhalational anaesthesia is the preferred mode of anesthesia for small duration cases. But in recent times, concept of rapid discharge, day care procedures, and green environment has created the need of new modalities of anaesthesia for such cases. Considering such factor, investigators have planned using TIVA i.e. total intravenous anaesthesia with Inj. Propofol and Inj. Dexmedetomidine infusions for maintenance of anesthesia in Modified Radical Mastectomy (MRM). By comparing the two modalities of anaesthesia i.e. TIVA vs Inhalational investigators are trying to find out whether TIVA is feasible, cost effective and comparable to inhalational anaesthesia in terms of intraoperative hemodynamic stability, pain, intraoperative awareness and recovery profile. This comparison and analysis will help to determine if TIVA can be used as the sole mode of anaesthesia during MRM as it will initiate early discharge of patient and will contribute to the Green OT concept.

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Rajiv Gandhi Cancer Institute & Research Center, India
• Treatments: Anesthetics; Dexmedetomidine; Nitrous Oxide; Propofol; Sevoflurane

Criteria

Inclusion Criteria:

• Age group: 30-65 yrs

• ASA status: 1-3

• Use of endotracheal tube for securing the airway

Exclusion Criteria:

• CKD, CLD patients

• Cardiac dysfunction

• Psychotic and neurotic disorders

• Drug addiction

• BMI > 30

• Use of supraglottic device

• Use of any nerve blocks