Overview

TIPPS: Thrombophilia in Pregnancy Prophylaxis Study

Status:
Completed
Trial end date:
2014-03-01
Target enrollment:
Participant gender:
Summary
The TIPPS trial seeks to determine the safety and effectiveness of low-molecular-weight heparin (LMWH), an anticoagulant, in preventing placenta mediated pregnancy complications and venous thromboembolism (VTE) in women with thrombophilia. Thus, the principal research question is: can LMWH prevent thrombosis in the leg veins, pulmonary arteries and placental vessels, thereby reducing the risk of deep vein thrombosis, pulmonary embolism (PE), intrauterine growth restriction (IUGR), preeclampsia, miscarriage and stillbirth?
Phase:
Phase 3
Details
Lead Sponsor:
Ottawa Hospital Research Institute
Collaborator:
Canadian Institutes of Health Research (CIHR)
Treatments:
Dalteparin
Heparin, Low-Molecular-Weight
Tinzaparin