Overview

TINI 2: Total Therapy for Infants With Acute Lymphoblastic Leukemia II

Status:
Not yet recruiting
Trial end date:
2033-12-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to improve upon the TINI study treatment. The study will test the ability of a type of immunotherapy called blinatumomab to clear persistent leukemia. Blinatumomab targets CD19 which is located on the leukemia cells outer membrane.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Stanford University
Collaborators:
Amgen
Lucile Packard Children's Hospital Foundation
Pediatric Oncology Experimental Therapeutics Investigators' Consortium
Treatments:
Asparaginase
Blinatumomab
Bortezomib
Dexamethasone
Mercaptopurine
Methotrexate
Mitoxantrone
Pegaspargase
Vorinostat