Overview

TESTO: Testosterone Effects on Short-Term Outcomes in Infants With XXY

Status:
Active, not recruiting
Trial end date:
2021-10-01
Target enrollment:
Participant gender:
Summary
This research study in infant males with Klinefelter syndrome (47,XXY) will learn more about the effect of testosterone on early health and development. The study is a total of three visits over 6 months with assessments of motor skills, body composition (muscle and fat), and hormone levels. This is a randomized, placebo-controlled study but all infants will receive testosterone treatment during the study period. The investigators will learn how testosterone treatment in infancy effects short term outcome measures on health and development.
Phase:
Phase 4
Details
Lead Sponsor:
University of Colorado, Denver
Collaborator:
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Treatments:
Methyltestosterone
Pharmaceutical Solutions
Testosterone
Testosterone 17 beta-cypionate
Testosterone enanthate
Testosterone undecanoate