TDCS and Cognitive Retraining to Augment Pharmacotherapy for the Treatment of Nicotine Dependence
Status:
Completed
Trial end date:
2018-03-31
Target enrollment:
Participant gender:
Summary
The purpose of the phase 1 translational pilot study proposed here is to gather preliminary
data investigating the efficacy of transcranial direct current stimulation (TDCS) and
cognitive retraining to enhance nicotine replacement therapy for smoking cessation. The
recent use of TDCS over task relevant regions to alter behavior holds incredible promise for
use in cognitive retraining intervention protocols. Previous studies of cognitive retraining
have focused on implicit training techniques. This proposed study will attempt to enhance
these implicit training techniques through the use of TDCS during implicit retraining in
order to increase learning of avoidance-related action tendencies towards tobacco. The
objective of this pilot study is to establish the feasibility and obtain preliminary data on
the effectiveness of using brain stimulation with cognitive retraining to reduce cigarette
smoking in individuals with nicotine addiction.