Overview

TAU-2014-1: Mibefradil and Hypofractionated Re-Irradiation Therapy in Recurrent GBM

Status:
Completed
Trial end date:
2017-09-29
Target enrollment:
Participant gender:
Summary
This is a dose-escalation study that will assess the safety and determine the maximum tolerated dose (MTD) of mibefradil dihydrochloride, a partially selective T-type calcium channel blocker, combined with hypofractionated radiation therapy (RT) in subjects with recurrent glioblastoma multiforme (GBM).
Phase:
Phase 1
Details
Lead Sponsor:
Cavion LLC
Jazz Pharmaceuticals
Collaborator:
Yale University
Treatments:
Mibefradil