TAPB vs QLBII for Kidney Transplantation Procedure

• Status: Completed
• Trial end date: 2017-05-30
• Target enrollment: 0
• Participant gender: All

Summary

The main advantage of Quadratus Lumborum Block (QLB) compared to Transversus Abdominalis Plane Block (TAPB) is the impact on visceral pain due to the spread of the local anaesthetic agent to the paravertebral space. It may produce extensive analgesia and better pain control.

Previews studies shoved the effectiveness of TAPB in kidney transplantation procedure (KTX) by reducing opioids requirements during and after the operation. QLB was not evaluating in KTX procedure yet, but it reduced postoperative morphine requirement after cesarean section under spinal anaesthesia.

The aim of this prospective, randomised controlled, multicenter, clinical study is to compare the perioperative analgesic efficacy of QLB and TAPB in patients who had KTX under balanced (general and regional) anaesthesia.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Medical University of Warsaw
• Treatments: Bupivacaine

Criteria

Inclusion Criteria:

1. Kidney transplantation procedure with anatomical urinary outlet

2. Written informed consent

Exclusion Criteria:

1. Patients' refusal

2. Known allergies to study medication

3. Inability to comprehend or participate in pain scoring scale

4. Inability to use intravenous patient controlled analgesia system

5. Anatomic, posttraumatic and postoperative deformations could possibly affect the spread of local anesthetic in transversus abdominalis plane or quadratus lumborum muscle plane.

6. Transversus abdominalis plane or quadratus lumborum muscle plane not seen in ultrasound examination.