TAP Block for Postoperative Pain Control

• Status: Terminated
• Trial end date: 2016-04-16
• Target enrollment: 0
• Participant gender: All

Summary

This clinical trial will examine differences in the effectiveness between three (3) commonly used methods and/or medications used to perform a transversus abdominis plane (TAP) block for post-operative pain control. The transversus abdominis muscle is either side between the lowest rib and the hip bone. Group A subjects will undergo post-operative pain relief treatment with a single injection of Bupivacaine injected into the TAP. Group B subjects will undergo post-operative pain relief treatment with a single injection of Exparel®, a liposomal form of bupivacaine into the TAP. Group C subjects will be treated with a continuous infusion of the local anesthetic ropivacaine with the ON-Q® pump. There will be no placebo group in this study.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Joshua Herskovic
• Treatments: Bupivacaine; Ropivacaine

Criteria

Inclusion Criteria:

• Ability to give written informed consent

• Scheduled for open abdominal surgery

• American Society of Anesthesiologists physical status 1 to 3

Exclusion Criteria:

• Inability to understand the study or provide written informed consent

• Inability to follow protocol instructions

• Complicated history of chronic opioid use including daily use of opioids for a period greater than 2 weeks prior to surgery

• Allergy to local anesthetic agents

• Contraindication to regional nerve block such as:

• Bleeding disorder

• Sepsis

• Infection at site of block

• Body Mass Index (BMI) >40

• Pregnancy