TAP Block With Plain Bupivacaine Versus Wound Infiltration With Exparel for Postoperative Pain Management

• Status: Completed
• Trial end date: 2015-02-01
• Target enrollment: 0
• Participant gender: Female

Summary

In this randomized, controlled, observer-blinded study we plan to evaluate pain relief after ultrasound-guided transversus abdominis plane (TAP) block using bupivacaine and wound infiltration using liposomal bupivacaine in patients undergoing abdominal hysterectomy.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Texas Southwestern Medical Center
• Treatments: Acetaminophen, hydrocodone drug combination; Bupivacaine

Criteria

Inclusion Criteria:

• Female

• ASA physical status 1-3

• Scheduled for open abdominal hysterectomy

• Age 18-80 years old

• Able to participate personally or by legal representative in informed consent in English or Spanish

Exclusion Criteria:

• History of relevant drug allergy

• Age less than 18 or greater than 80 years

• Chronic opioid use or drug abuse

• Significant psychiatric disturbance

• Inability to understand the study protocol

• Refusal to provide written consent