Overview

T-DM1 and Osimertinib Combination Treatment to Target HER2 Bypass Track Resistance in EGFR Mutation Positive NSCLC

Status:
Recruiting
Trial end date:
2022-04-01
Target enrollment:
Participant gender:
Summary
This is a single arm open-label multi-center phase II study, investigating disease control rate after 3 months of treatment with trastuzumab-emtansine/osimertinib combination therapy in patients with advanced EGFR mutation positive non-small cell lung cancer (NSCLC) with HER2 bypass track resistance.
Phase:
Phase 2
Details
Lead Sponsor:
The Netherlands Cancer Institute
Collaborators:
AstraZeneca
Roche Pharma AG
Treatments:
Ado-Trastuzumab Emtansine
Maytansine
Osimertinib
Trastuzumab