Systolic Hypertension in the Elderly Program (SHEP) (Pilot Study)
Status:
Completed
Trial end date:
1983-05-01
Target enrollment:
Participant gender:
Summary
The SHEP Pilot Study had six objectives, each designed to develop and test critical
components of a full scale trial directed at the health consequences of treating isolated
systolic hypertension (ISH) in the elderly.
l. To estimate and compare the yield of participants for randomization into a clinical trial
from various community groups using various recruitment techniques.
2. To estimate compliance with the visit schedule and to the prescribed double-blind
regimens.
3. To estimate and compare the effectiveness of specified antihypertensive medications in
reducing the blood pressure.
4. To estimate and compare the unwanted effects of specified antihypertensive medication in
an elderly population.
5. To evaluate the feasibility and effectiveness of periodic behavioral assessment in this
population.
6. To develop and test methods of ascertaining stroke and other disease endpoints.