Systemic and Local Antimicrobials in the Management of Dental Abscess in Children
Status:
Completed
Trial end date:
2020-02-13
Target enrollment:
Participant gender:
Summary
Dental infections originating in the teeth are routinely managed systemically with a course
of oral antibiotics, while severe forms are managed with intravenous antibiotics. Dental
infections can also be managed by removing the offending cause of the infection followed by
placement of an intra-canal medication which acts as a local antimicrobial. Intra-canal
medicaments are being used in clinical practice following root canal treatment. The
investigators hypothesize that the effect of intra-canal antimicrobials in the management of
dental infections will be the better than oral antibiotics in terms of clinical , microbial
and oral- health quality of life parameters. This will be a three-arm, parallel, comparative,
randomized study with the aim of assessing the efficacy of intra-canal medication and oral
antibiotics in reducing the infection and treatment of odontogenic infections, based on signs
and symptoms and microbial count. The study will be performed in child participants between
the age group of 3 to 11 years presenting with acute odontogenic infections. Participants
will be randomized by block randomization. The treatment duration of the study will be at
least 5 days or maximum 7 days depending upon the response. Participants will be assessed on
Day 3 and Day 5/7. Concurrently, the oral health-related quality of life (OHRQoL) following
these clinical interventions in children will be recorded and again on Day 14. Quantitative
assessment of microorganisms seen in the root canals and the changes seen in the microbial
flora through the treatment will help us to determine the best antimicrobial agent to be used
in the management of odontogenic infections.