Overview

Systemic Immunomodulatory Effects and Pharmacogenetics of Atorvastatin in Early Atherosclerosis

Status:
Completed
Trial end date:
2009-01-01
Target enrollment:
0
Participant gender:
All
Summary
The purpose of the study is to test whether atorvastatin (also known as Lipitor) has anti-inflammatory effects in people with no known heart disease or high cholesterol. We also are investigating whether or not genetic differences between people plays a role in the drug response.
Phase:
Phase 4
Accepts Healthy Volunteers?
Accepts Healthy Volunteers
Details
Lead Sponsor:
University of Florida
Collaborators:
American College of Clinical Pharmacy
American Heart Association
Treatments:
Atorvastatin
Atorvastatin Calcium
Criteria
Inclusion Criteria:

- 18+ years old

- Normocholesterolemic

Exclusion Criteria:

- Cardiovascular disease or risk equivalents

- Malignancy

- Active alcohol abuse

- Contraindications to statins

- Interacting drugs

- Chronic anti-inflammatory drugs