Synaptic Imaging and Network Activity in Treatment Resistant Depression
Status:
Recruiting
Trial end date:
2023-09-11
Target enrollment:
Participant gender:
Summary
The main aim of this research is to explore the effects that ketamine has on the functional
connectivity of the brain in participants with treatment resistant depression (TRD). This
study will investigate the relationship between these changes and response to treatment as
measured by clinical scales, as well as examining drug induced changes in reward and emotion
based brain activity, structural connectivity, cerebral blood flow, cognition, metabolism and
blood markers of brain plasticity.