Symptom Assessment for Patients With Gastro-esophageal Reflux Disease Receiving Helicobacter Pylori Eradication
Status:
Unknown status
Trial end date:
2019-09-01
Target enrollment:
Participant gender:
Summary
Background: Rebound acid hypersecretion and acid-related symptoms after discontinuation of
proton-pump inhibitor has been reported in previous studies. In patients with concurrent
gastro-esophageal reflux disease and Helicobacter pylori infection, whether eradication of H.
pylori will aggravate acid-related symptoms after discontinuation of proton-pump inhibitor
(PPI) remains elusive Objective: This study aims to investigate the incidence and severity of
acid-related symptoms after discontinuation of proton-pump inhibitor in reflux patients
receiving H. pylori eradication Expected result: The investigators will find out the
incidence and severity of acid-related symptoms after discontinuation of proton-pump
inhibitor in reflux patients receiving H. pylori eradication