Surgical Protocol for Treatment of Peri-implantitis

• Status: Not yet recruiting
• Trial end date: 2019-07-01
• Target enrollment: 45
• Participant gender: All

Summary

Peri-implantitis are important disease entities as a result of their high prevalence and the lack of a standard mode of therapy.

Based on the available data, the non-surgical therapy of peri-implantitis doesn't seem to be effective in disease resolution. Surgical access to peri-implantitis lesions facilitates the removal of all granulation tissue from the defect area as well as a thorough debridement and decontamination of exposed implant surfaces.

Numerous approaches have been used for implant surface decontamination during peri-implant surgery, including mechanical, chemical and laser treatments.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Università Vita-Salute San Raffaele
• Treatments: Chlorhexidine; Chlorhexidine gluconate

Criteria

Inclusion Criteria:

• presence of at least one screw-type titanium implant exhibiting bleeding and/or suppuration on probing combined with a PPD ≥ 5 mm and bone loss ≥ 2 mm (compared to crestal bone levels at the time of placement of the reconstruction)

• single tooth and bridgework restorations without overhangings

• no evidence of occlusal overload (i.e. occlusal contacts revealed appropriate adjustment),

• treated chronic periodontitis and proper periodontal maintenance care

• FMPS < 20%

• non-smoker or light smoking status in smokers (<10 cigarettes per day)

• implant function time ≥ 1 year.

Exclusion Criteria:

• Patients with uncontrolled diabetes,

• patients with osteoporosis or under bisphosphonate medication,

• pregnant or lactating women,

• patients with a history of radiotherapy to the head and neck region

• patients with incapability to perform basal oral hygiene measures due to physical or mental disorders

• hollow implants

• implant mobility

• implants at which no position could be identified where proper probing measurements could be performed;

• previous surgical treatment of the peri-implantitis lesions