Overview

Surgical Excision and Intralesional Steroid Injection for Prevention of Post Caesarean Keloid Recurrence

Status:
Completed
Trial end date:
2018-01-24
Target enrollment:
0
Participant gender:
Female
Summary
Two groups of patients (73 patients each) undergoing routine caesarean section has recurrent keloid at site of surgical scar. One group will undergo surgical excision of keloid. The other group will have combined surgical excision of keloid and single intralesional dexamethasone injection at edges of wound.All patients were reviewed once per month for 6 months for evidence of recurrence
Phase:
Phase 4
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Kasr El Aini Hospital
Treatments:
BB 1101
Dexamethasone
Dexamethasone acetate
Criteria
Inclusion Criteria:

- Documented keloids of pfannenstiel incision or midline subumbilical incision of one to
five years duration.

- Previous treatment of keloid and recurrence.

- Patient complaint of cosmetic disfiguring, pain or pruritis at site of scar.

Exclusion criteria:

- Scar <1 years' duration

- Scar extending beyond the limits of the original lesion

- postburn keloids

- Diabetes Mellitus, anaemia (haemoglobin level <10mg/dL), malignancy, malnutrition.

- local inflammation at site of scar

- Allergy to dexamethasone.

- Immunocompromized patients or patients on chronic steroid treatment.