Surgery and Oxaliplatin or Mitomycin C in Treating Patients With Tumors of the Appendix
Status:
Completed
Trial end date:
2016-11-01
Target enrollment:
Participant gender:
Summary
This randomized phase II trial is studying the side effects and how well giving oxaliplatin
or mitomycin C directly into the abdomen after surgery works in treating patients with tumors
of the appendix. Drugs used in chemotherapy, such as oxaliplatin and mitomycin C, work in
different ways to stop the growth of tumor cells, either by killing the cells or by stopping
them from dividing. Heating a chemotherapy solution and infusing it directly into the abdomen
may kill more tumor cells. Giving these treatments after surgery may kill any tumor cells
that remain after surgery.