Overview

Surgery Vs Chemoradiation for Oropharyngeal Cancer- A Phase II/III Integrated Design Randomized Control Trial

Status:
Not yet recruiting

Trial end date:
2031-06-30

Target enrollment:

Participant gender:

Summary

The oropharyngeal areas mainly comprises of the tonsil, base tongue (BOT), soft palate and the posterior pharyngeal wall. Traditionally, surgical resection of oropharyngeal cancers (OPC) was a standard procedure, often performed through mutilating incisions with mandibulotomies, rendering significant post-operative functional deficits. Over the past 2 decades, there has been a major shift in treatment strategy with a majority of these cancers now being treated by primary concurrent chemoradiation (CCRT) with a trend towards organ and function preservation.

Phase:

Phase 2/Phase 3

Details

Lead Sponsor:

Tata Memorial Centre

Collaborators:

All India Institute of Medical Sciences, New Delhi
Amrita Institute of Medical Sciences & Research Center

Treatments:

Cisplatin