Surgery Plus Single Agent Chemotherapy Versus Primary Chemotherapy for Gestational Trophoblastic Neoplasms

• Status: Unknown status
• Trial end date: 2017-08-01
• Target enrollment: 0
• Participant gender: Female

Summary

Gestational trophoblastic neoplasm affect women and is sensitive to chemotherapy especially methotrexate and the investigators try to find a role of surgery plus methotrexate instead of multiple doses and cycles of chemotherapy.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Maher elesawi kamel elesawi
• Treatments: Calcium, Dietary; Folic Acid; Leucovorin; Levoleucovorin; Methotrexate

Criteria

Inclusion Criteria:

• females

• 40 years or more

• plateau or rising B- hCG titre

• without distant metastasis

• WHO score is less than 7

Exclusion Criteria:

• less than 40 years

• distant metastasis to lung and liver

• chronic medical diseases

• WHO score is more than 7