Overview

Surgery Followed by Risk-Directed Post-Operative Adjuvant Therapy for HPV-Related Oropharynx Squamous Cell Carcinoma: "The Minimalist Trial (MINT)"

Status:
Active, not recruiting

Trial end date:
2026-03-10

Target enrollment:

Participant gender:

Summary

The overarching goal of the MINT trial is to reduce treatment-related toxicity while maintaining efficacy. Patients with HPV-related oropharyngeal squamous cell carcinoma (OPSCC) will undergo resection of the primary tumor site and involved/at risk regional neck nodes.

Phase:

Phase 2

Details

Lead Sponsor:

Washington University School of Medicine

Treatments:

Cisplatin