Overview

Supplemental Thyroxine Treatment for Preterm Infants With Hypothyroxinemia

Status:
Completed
Trial end date:
2013-06-01
Target enrollment:
0
Participant gender:
All
Summary
In order to determine the efficacy and safety of thyroxine replacement, a randomized clinical trial of thyroxine supplementation for VLBW infant with hypothyroxinemia during the first month of age is conducted.
Phase:
N/A
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Tokyo Women's Medical University
Collaborator:
Tokyo Metropolitan Bokuto Hospital
Criteria
Inclusion Criteria:

- Birth weight: less than 1500g

- Gestation: 22 weeks 0 day ≤

- Serum free thyroxine level lower than 0.8 ng/dl

- Serum thyrotropin lower than 10 μU/ml

- Age of between 2 and 4 weeks after birth

- Informed consent

Exclusion Criteria:

- any known thyroid disease in mother